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  5. Neutralization of interleukin-22 blocks the recruitment of non-specific cells into the liver without

Neutralization of interleukin-22 blocks the recruitment of non-specific cells into the liver without

来源 :2014年APASL专题会议暨第四届乙型病毒性肝炎专题会议 | 被引量 : 0次 | 上传用户：ccsrg
【摘 要】
：
Background:Th17 cells secreting interleukin(IL)-22 displays immunodulotory and protective properties in the liver and other tissues.IL-22 induces proinflammatory gene expression is mitogenic and antia
【作 者】
：
Ye Zhang Jianqi Lian Changxing Huang Ying Zhang Michael Robek Xuefan Bai 
【机 构】
：
Center of Infectious Diseases,Tangdu Hospital,Fourth Military Medical University
【出 处】
：
2014年APASL专题会议暨第四届乙型病毒性肝炎专题会议
【发表日期】
：
2014年4期
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Background:Th17 cells secreting interleukin(IL)-22 displays immunodulotory and protective properties in the liver and other tissues.IL-22 induces proinflammatory gene expression is mitogenic and antiapoptotic,it may perform multiple roles in the immune response to hepatitis B virus(HBV).Methods:We therefore examined the IL-22 expression in HBV infected patients in vitro by flow cytometry and ELISA.The effect of IL-22 on inflammatory regulation in vivo was also measured using HBV transgenic mice.
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