【摘 要】
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Endogenous retroviruses in the human DNA probably result from an exogenous infection of germ line cells during primate evolution nearly 25 million years ago.ERV-W copies are present in old world monke
【机 构】
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Development Officer Geneuro SA Switzerland
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Endogenous retroviruses in the human DNA probably result from an exogenous infection of germ line cells during primate evolution nearly 25 million years ago.ERV-W copies are present in old world monkeys, superior primates and in humans (then named HERV-W).HERV-W encodes and may express an envelope protein (Env), which activates a pro-inflammatory and autoimmune cascade through interaction with Toll-Like receptor 4 on antigen-presenting cells.
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