【摘 要】
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MCPH1/microcephalin is proposed to function in ATM- and ATR-mediated DNA damage response (DDR),and controls cell cycle progression and genomic stability.After i
【机 构】
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LeibnizInstituteforAgeResearch-FritzLipmannInstitute,Jena,GermanyInstituteofMolecularCellBiology,Cen
论文部分内容阅读
MCPH1/microcephalin is proposed to function in ATM- and ATR-mediated DNA damage response (DDR),and controls cell cycle progression and genomic stability.After ionizing and UV irradiation,MCPH1 colocalizes with several key components of DDR,including 53BP1,MDC1,NBS1,and RPA,as well as Chk1 and BRCA1.
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