【摘 要】
：
2-Arylidene-1,3-indane-diones are highly reactive α,β-unsaturated carbonyl compounds and have been extensively used as 1,3-dipolarophiles,dienophiles and active alkenes in many cycloaddition,Michael a
【机 构】
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College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, China
【出 处】
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中国化学会第十三届全国有机合成化学学术研讨会
论文部分内容阅读
2-Arylidene-1,3-indane-diones are highly reactive α,β-unsaturated carbonyl compounds and have been extensively used as 1,3-dipolarophiles,dienophiles and active alkenes in many cycloaddition,Michael addition and condensation reactions.There have been some reports about the cycloaddition reaction of heterocyclic nitrogen ylides with 2-arylidene-1,3-indanediones to give spiro[cyclopropane-1,2-inden]-1,3-diones,dihydroindeno[1,2-b]furans and spiro[benzo[d]pyrrolo[2,1-b]thiazole-3,2-indenes].1 However,we found that three-component reaction of N-butyl-N-phenacylbenzimidazolium bromide,aromatic aldehydes and 1,3-indanedione in ethanol in the presence of triethylamine as base catalyst resulted in the unusual charge-separated zwitterionic salts in good yields.Furthermore,1H NMR spectra and single crystal structures indicated that the zwitterionic salts usually exist in two kinds of conformation isomers due to hindered interconvert of the different conformations.
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