全球治疗模式下的误用、滥用及挪用

来源 :第四届中国酒精与药物滥用研讨会、第三届亚太酒精与成瘾学会会议 | 被引量 : 0次 | 上传用户:wangruiqiangkang
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大量的文献报道认为对阿片类物质依赖者进行治疗是一个性价比高的选择,可以减少物质依赖所导致的一些危害,且治疗与非治疗后果完全不同.由于患者当中HIV感染的阳性率逐渐增加,在过去的20-30年当中,越来越多的国家开始给阿片类物质依赖者提供治疗,但是不同国家的治疗方法千差万别.有的国家认为阿片类依赖是一个社会问题,把依赖者当作罪犯去给与"治疗",有的国家认为阿片类物质依赖与糖尿病一样,属于慢性复发性疾病,提供长期的维持治疗.
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背景:炎症细胞因子的激活可能与阿片类物质依赖的形成有关.本研究中,我们评估炎症因素是否与阿片物质成瘾有关.并进一步研究低剂量美金刚合并抗炎药对接受美沙酮维持治疗的海洛因依赖者的效果.方法:采用12周的双盲、随机、对照试验.定期接受美沙酮维持治疗的患者被随机分为:美金刚组(5mg/天)(n=50)或安慰剂组(n=75).在第0、1、4、8和12周检测美沙酮剂量需求和血浆细胞因子.结果:经过12周的治
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