The Effect on Induced Pluripotent Stem Cell of The Extract of Akermanite in Vitro

• 作 者: DongXixi;DuQinghua;WeiLijun;ELingling;CaoJunkai;
• 机 构: Department of Stomatology,Chinese PLA General Hospital
• 出 处: 2014xi`an Conference of International Society for Maxillofac
• 发表日期: 2014年期

　　Purpose: To assess the ability of iPS cells to differentiate into bone in vitro.Methods: Use the different diluted rate extract to induce ipsc,MTT analysis were used to reveal the proliferation.Expression level of osteogenic differentiation genes(ALP、BSP、OCN)were examined at 7、14 and 21 days.Results: 1/2 extract has the better efficiency in osteogenic differentiation.Conclusion: The exract of Akermanite has the ability to induce ipsc into bone,and ipsc with its scaffolds have a great potential in application in engineered bone.