Properties of a co-processed compound versus the physical blend based on lactose and microcrystallin

来源 :首届亚洲药物制剂科学研讨会(1st Asian Pharmaceutical Science and Technolog | 被引量 : 0次 | 上传用户：jack_123456

【摘要】

：

【作者】

：

Yan Hu Ling Zhang Jingbin Cui

【机构】

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College of Pharmacy, East China University of Science and Technology, Shanghai

【出处】

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首届亚洲药物制剂科学研讨会(1st Asian Pharmaceutical Science and Technolog

【发表日期】

：

2007年12期

【关键词】

：

lactose MCC recrystallization direct compression

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　　Purpose A new co-processed compound made of lactose and microcrystalline cellulose (MCC) was prepared for direct compression.Methods The properties of the compound has been compared to that of the physical blend.Results The compound exhibited good flowability, compressibility and shorter disintegration time.Conclusion The compound was superior to physical blend in direct compression.

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Properties of a co-processed compound versus the physical blend based on lactose and microcrystallin

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