Effects of process parameters on characteristics and internal morphology of poly(D,L-lactide-co-glyc

来源 :首届亚洲药物制剂科学研讨会(1st Asian Pharmaceutical Science and Technolog | 被引量 : 0次 | 上传用户：bjbysj44

【摘要】

：

【作者】

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Shirui Mao Yi Shi Luk Li Jing Xu Andreas Schaper Thomas Kissel

【机构】

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School of Pharmacy, Shenyang Pharmaceutical University, 103 Wenhua Road, Shenyang, 110016, China;Dep

【出处】

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首届亚洲药物制剂科学研讨会(1st Asian Pharmaceutical Science and Technolog

【发表日期】

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2007年12期

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　　Taking ABT627 as a hydrophobic model drug, poly-(lactic-co-glycolic acid) (PLGA) microspheres were prepared by an emulsion solvent evaporation method.Internal morphology of the microspheres was observed with scanning electron microscopy by stereological method.It was found that hydrophobic drug release from the PLGA microspheres is mainly dependent on the internal morphology and drug distribution state in the microspheres.

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Effects of process parameters on characteristics and internal morphology of poly(D,L-lactide-co-glyc

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