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Life is a biochemical process that has evolved in relation to the thermal conditions on our planet.In warmblooded animals, this biochemical processes of life have been optimized over a narrow temperature range of a few degrees centigrade.Reducing the temperature of the celles/tissues of warm-blooded animals and human has two conflicting effects.On one hand, a reduction in chemical reaction rates slows down life processes and can preserve organisms and tissues.However, on the other hand, the disruption of the evolutionary optimized chemical paths al so induces imbalance and damage.These two aspects of reduced temperatures are of great importance in modern medicine and biotechnology.