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The recently identified innate lymphoid cell (ILC) family consists of interferon-γ (IFN-γ-secreting group 1 ILCs (ILC1), type-2 cytokine-producing ILC2s and IL-22 and/or IL-17-positive ILC3s.ILC1 and ILC3 play critical roles in protective immunity against bacteria, intracellular protozoan parasites (ILC1), and fungi (ILC3), and in autoimmune disorders.By contrast ILC2 associate with immune responses to parasitic worms and allergy.