LMA-1 maintains lysosome integrity for normal larval development and adult life span

来源 :The 7th International Symposium on Autophagy 2015(第七届自噬国际研讨会 | 被引量 : 0次 | 上传用户：jh_fan88

【摘要】

：

Lysosomes are specialized membrane bound organelles that degrade macromolecular cargoes derived from endocytosis, phagocytosis or autophagy.The resulting catabo

【作者】

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Yuan Li Wei Zou Baohui Chen Yanan Sun Xiaochen Wang

【机构】

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NationalInstituteofBiologicalSciences,No.7ScienceParkRoad,ZhongguancunLifeSciencePark,Beijing,102206

【出处】

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The 7th International Symposium on Autophagy 2015(第七届自噬国际研讨会

【发表日期】

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2015年3期

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Lysosomes are specialized membrane bound organelles that degrade macromolecular cargoes derived from endocytosis, phagocytosis or autophagy.The resulting catabolites are exported by membrane transporters on lysosomes for re-utilization in cellular metabolism.Over 50 human disorders have been identified due to dysfunctions of lysosomes, indicating important roles of lysosomes in cell homeostasis and animal development.

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LMA-1 maintains lysosome integrity for normal larval development and adult life span

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