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Classical swine fever(CSF),caused by classical swine fever virus(CSFV),is a highly contagious,often fatal porcine disease with significant economic losses.CSFV,together with bovine viral diarrhea virus(BVDV)and border disease virus(BDV),form the genus Pestivirus within the family Flaviviridae,which hepatitis C virus(HCV)also belongs to.