EPHA2 IS A HOST FACTOR FOR EPSTEIN-BARR VIRUS INFECTION OF NASOPHARYNGEAL EPITHELIAL CELLS

来源 :17th International Workshop on Kaposi’s Sarcoma Associated H | 被引量 : 0次 | 上传用户：jianghulong007

【摘要】

：

Epstein-Barr virus (EBV) has been causally associated with lymphoid and epithelial malignancies, suggesting its primary tropisms for these two types of cells.Th

【作者】

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Hua Zhang Hong-Bo Wang Yan Li Yong Du Dan Xiong Qian Zhong Wan-Li Liu Man-Zhi Li Wen-Lin Huang Song Gao Lindsey M Hutt-Fletcher Yi-Xin Zeng Elliott Kieff Mu-Sheng Zeng

【机构】

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SunYat-senUniversityCancerCenter,ChinaLouisianaStateUniversity,USAHarvardMedicalSchool,USA

【出处】

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17th International Workshop on Kaposi’s Sarcoma Associated H

【发表日期】

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2014年7期

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Epstein-Barr virus (EBV) has been causally associated with lymphoid and epithelial malignancies, suggesting its primary tropisms for these two types of cells.The complement receptor type 2 (CR2) has been identified as the receptor mediating EBV infection of B lymphocytes for almost three decades.However, in the epithelial cells, there are no functional receptors identified so far.One of the key hurdles is the lack of efficient in vitro epithelial infection model.

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EPHA2 IS A HOST FACTOR FOR EPSTEIN-BARR VIRUS INFECTION OF NASOPHARYNGEAL EPITHELIAL CELLS

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