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BACKGROUND: Malnutrition is one of the common complications of chronic obstructive pulmonary disease (COPD).This study aimed to evaluate the influences of exercise combined with nutrition support on COPD complicated with malnutrition.METHODS: Two-hundred and twety-eight cases of COPD were enrolled, and 80 cases (aged 69.28 ± 9.42 years) complicated with malnutrition were selected.According to the treatment time, 80 cases were randomly divided into two groups.On the basis of routine therapy, the patients in treatment group were treated with exercise combined with nutrition support for 6 months, while the patients in control group were treated with routine therapy only.All the patients received FEV1%, 6 min walking distance (6MWD) and happiness satisfaction examination before and after the treatment.