Crystal structure of Rot, a global regulator of virulence genes in Staphylococcus aureus

• 作 者: 朱玉威;范晓娇;滕脉坤;李旭;
• 机 构: 中国科学技术大学
• 出 处: 中国生物化学与分子生物学会第十一次会员代表大会暨2014年全国学术会议
• 发表日期: 2014年期

　　Staphylococcus aureus is a highly versatile pathogen that can infect the tissue ofhuman by producing a large arsenal of virulence factors, which was tightly regulated by acomplex regulatory network.Rot, sharing sequence similarity to SarA homologues, is aglobal regulator that regulates numerous virulence genes.