Synaptic plasticity in rat retina following optic nerve injury

• 作 者: Xue-GangLUO;DanCHEN;YanCAI;En-DongZHANG;Xiao-ShengWANG;HuiWANG;Ju-FangHUANG;
• 机 构: Department of Human Anatomy and Neurobiology, Xiangya School of Medicine, Central South University,
• 出 处: 中国神经科学学会第四次会员代表大会暨第七届全国学术会议(The 7th Biennial Meeting and the
• 发表日期: 2007年期

　　It is said that the retinal ganglion cells (RGCs) following optic nerve injury can be regenerated by peripheral nerve transplantation and/or neurotrophins supplement.The new generating axons of RGCs can reach their target area and rebuild synaptic connections with neurons in superior colliculus or lateral geniculate nucleus.Nevertheless,the visual function,especially the accurate vision,can not recover completely.It should be concerned that changes of the integrity of structure and function of visual pathway within retina may be involved in this process.