【摘 要】
：
Pneumocystisjiroveci (formerly carinii) pneumonia (PCP) is still a common AIDS-defining disease and cause of mortality in HIV-infected persons.Conventional treatments,trimethoprim-sulfamethoxazole (Tm
【机 构】
：
FRCP(C)Department of Microbiology & Immunology-University of Montreal and Department of Microbiology
【出 处】
：
2006中国天津世界艾滋病日科技会议
论文部分内容阅读
Pneumocystisjiroveci (formerly carinii) pneumonia (PCP) is still a common AIDS-defining disease and cause of mortality in HIV-infected persons.Conventional treatments,trimethoprim-sulfamethoxazole (Tmp/Srnx) and pentanidine,are effective in 80-96% of cases but carry a high risk of drug-related adverse events.Moreover,increasing rates of sulpha allergy or intolerance are encountered.The combination of clindamycin with prinaquine (Cm/Prq) is known for its anti-PCP effects since 1998.In addition both,2 components have an effect on Plasmodium species.
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