【摘 要】
:
In light of the ability of HIV-1 to escape anti-HIV-1 therapeutics,there is a need to identify compounds that are structurally and mechanistically distinct from the products currently under developmen
【机 构】
:
Center for AIDS Research,Duke University Medical Center, USA
【出 处】
:
2006中国天津世界艾滋病日科技会议
论文部分内容阅读
In light of the ability of HIV-1 to escape anti-HIV-1 therapeutics,there is a need to identify compounds that are structurally and mechanistically distinct from the products currently under development.We have chemically modified the natural product betulinc acid to obtain potent anti-HIV-1 agents with novel mechanisms of action.
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