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  5. A pH sensitive carboxymethyl cellulose-g-poly (acrylic acid)/polyvinylpyrrolidone/sodium alginate co

A pH sensitive carboxymethyl cellulose-g-poly (acrylic acid)/polyvinylpyrrolidone/sodium alginate co

来源 :The Third Symposium on Innovative Polymers for Controlled De | 被引量 : 0次 | 上传用户：mervin10183
【摘 要】
：
Design and development of multi-component polymer materials for controlled drug release has become a subject of great interests [1].In this work,a new semi-IPN hydrogel composed of carboxymethyl cellu
【作 者】
：
Qin Wang Wenbo Wang Aiqin Wang 
【机 构】
：
Center of Eco-material and Green Chemistry,Lanzhou Institute of Chemical Physics,Chinese Academy of
【出 处】
：
The Third Symposium on Innovative Polymers for Controlled De
【发表日期】
：
2014年6期
【关键词】
：
carboxymethyl cellulose polyvinylpyrrolidone multi-component semi-IPN polymer hy 
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　　Design and development of multi-component polymer materials for controlled drug release has become a subject of great interests [1].In this work,a new semi-IPN hydrogel composed of carboxymethyl cellulose-g-poly(acrylic acid)/polyvinylpyrrolidone (CMC-g-PAA/PVP) was synthesized by solution polymerization as a carrierfor diclofenac sodium (DS) [2].However,results showed burst DS release from CMC-g-PAA/PVP hydrogels at pH 6.8.It is known that sodium alginate (SA) can form a reticulated structure in the presence of Ca2+.
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