【摘 要】
：
With the accumulation of multi-scale and large data in mental disorders, we are in the unprecedented position of potentially finding out the roots of many disea
【出 处】
：
第三届数学、计算机与生命科学交叉研究青年学者论坛
论文部分内容阅读
With the accumulation of multi-scale and large data in mental disorders, we are in the unprecedented position of potentially finding out the roots of many diseases, using both modelling and data mining approaches.In the talk, we will first review the current situation we are facing.A few successful examples to illustrate how we can combine efforts from medical science (collecting data), biology(exploring mechanisms), computer science (visualization), statistics(mining data) and mathematics (modelling) to tackle diseases such as schizophrenia, depression and autism.Finally, the implications of our work in current Brain projects and applications are also briefly summarized.
其他文献
In shotgun proteomics, high-throughput mass spectrometry experiments and the subsequent data analysis produce thousands to millions of hypothetical peptide iden
心肌细胞是心脏收缩和舒张的基本结构单元,由肌膜/横管、肌质网、肌纤维、线粒体、细胞核等多种细胞器构成.心肌细胞及其亚细胞结构是维持心脏正常工作的结构基础.在多种原因
With the rapid accumulation of microbial community samples and related metagenomic sequencing data, data integration and analysis system is urgently needed for
With the rapid increase in the amount of published information or data, information retrieval has been widely utilized in many applications, such as web searchi
Differentially expressed, cell type-specific gene sets are pivotal to multiple important problems in developmental biology.Individual cell types of interest hav
Pathway or gene set over-representation analysis (ORA) has become a routine task in functional genomics studies.However, currently widely used ORA tools employ
Metastasis of breast cancer leads to high mortality, and accurate prognosis of metastasis is critical for effective intervention.In this talk, Ill present a new
N6-methyladenosine (m6A) has been recently identified as a conserved epitranscriptomic modification of eukaryotic mRNAs, but its features,regulatory mechanisms,
Exon circularization has been identified from many loci in mammals, but the detailed mechanism of its biogenesis has remained elusive.By using genome-wide appro