Study on miRNA-200c delivery systems for breast cancer stem cell therapy

来源 :2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会 | 被引量 : 0次 | 上传用户：napone

【摘要】

：

　　One of the biggest obstacles towards treatment of breast cancer is breast cancer stem cells (BCSC), which have the properties of self-renewal and differenti

【作者】

：

JingwenLiu;TingtingMeng;HongYuan;FuqiangHu;

【机构】

：

College of Pharmaceutical Science, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058,P.R.Chi

【出处】

：

2015年中国药物制剂大会、中国药学会药剂专业委员会2015年学术年会暨国际控释协会中国分会2015年学术年会

【发表日期】

：

2015年期

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　　One of the biggest obstacles towards treatment of breast cancer is breast cancer stem cells (BCSC), which have the properties of self-renewal and differentiation.It has been reported that miRNA-200c is significantly downregulated in BCSCs as compared with non-tumorigenic cells.Scientific researches revealed that miRNA-200c can inhibit the clonogenicity of BCSCs, suppress the cancer cell growth and tumor formation driven by human BCSCs in vivo.

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Study on miRNA-200c delivery systems for breast cancer stem cell therapy

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