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  5. ERK inhibition sensitizes cancer cells to oleanolic acid-induced apoptosis through ERK/Nrf2/ROS path

ERK inhibition sensitizes cancer cells to oleanolic acid-induced apoptosis through ERK/Nrf2/ROS path

来源 :第十二次全国营养科学大会 | 被引量 : 0次 | 上传用户：marrylosa123
【摘 要】
：
Objectives This study is aimed to explore the role of ERK for the antitumor activity of oleanolic acids.Methods Cell culture,siRNA transfection,Immunoblotting assay,Apoptosis detection,ROS detection,A
【作 者】
：
LIU JIA MA LEINA CHEN XIAO LIANG HUI LIN XIUKUN 
【机 构】
：
College of Medicine,Qingdao University,Qingdao 266021,China
【出 处】
：
第十二次全国营养科学大会
【发表日期】
：
2015年5期
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Objectives This study is aimed to explore the role of ERK for the antitumor activity of oleanolic acids.Methods Cell culture,siRNA transfection,Immunoblotting assay,Apoptosis detection,ROS detection,Animal experiments Results In this study,we found that OA induced the activation of ERK in cancer cells.
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