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  5. The monitoring and preventing of spinal cord ischemic injury during thoracic descending aortic opera

The monitoring and preventing of spinal cord ischemic injury during thoracic descending aortic opera

来源 :第七届北京五洲心血管病研讨会 | 被引量 : 0次 | 上传用户：buerzui
【摘 要】
：
Background A model of ischcmic injury to the spinal cord was established in pigs by clamping the thoracic descending aorta.The feasibility of monitoring spinal-cord ischemia using the cortical somatos
【作 者】
：
Feng Liu Yulong Guan Caihong Wan Peiqing Dong 
【机 构】
：
Extracorporeal Circulation Department, Beijing Anzhen Hospital, Capital Medical University, Beijing.
【出 处】
：
第七届北京五洲心血管病研讨会
【发表日期】
：
2013年12期
【关键词】
：
cortical somatosensory evoked potentials spinal cord ischemia paralysis parapleg 
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　　Background A model of ischcmic injury to the spinal cord was established in pigs by clamping the thoracic descending aorta.The feasibility of monitoring spinal-cord ischemia using the cortical somatosensory evoked potential (CSEP) was evaluated.Outcomes between the simple clamp (SC) group and left-heart bypass (LHB) group were compared.Methods Twelve mini-pigs were randomly divided into two groups SC group and LHB group randomly.The left intercostal incision was adopted.The thoracic descending aorta was clamped under the left irmominate artery outlet.CSEP was recorded to monitor the function of the spinal cord.The behavior score was observed every day after surgery.Mini-pigs were killed on the seventh postoperative day.Ultrastructural changes were observed by transmission electron microscopy.
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