【摘 要】
：
目的 本研究旨在定量描述起始胰岛素治疗的2型糖尿病患者对胰岛素的依从性与持续用药性,并识别其影响因素.方法 本研究基于天津城镇职工基本医疗保险2008-2011年数据.2009-2010年间初始使用胰岛素,初始治疗前12个月(基线期)及后12个月(随访期)持续参保的2型糖尿病患者被纳入研究.研究采用药物持有率(MPR)描述依从性,MPR≥80％的患者被识别为随访期内药物依从.
【机 构】
：
天津大学药物科学与技术学院 天津医科大学代谢病医院
【出 处】
：
中华医学会第十四次全国内分泌学学术会议
论文部分内容阅读
目的 本研究旨在定量描述起始胰岛素治疗的2型糖尿病患者对胰岛素的依从性与持续用药性,并识别其影响因素.方法 本研究基于天津城镇职工基本医疗保险2008-2011年数据.2009-2010年间初始使用胰岛素,初始治疗前12个月(基线期)及后12个月(随访期)持续参保的2型糖尿病患者被纳入研究.研究采用药物持有率(MPR)描述依从性,MPR≥80％的患者被识别为随访期内药物依从.
其他文献
目的 在前期研究基础上,探讨可导致迟发DM的突变前胰岛素原R6C和R6H的无效转位导致β细胞衰竭和DM的分子机制方法 1在有无MG132处理下,用35S-Met/Cys标记追踪转染R6C/A24D的293T,INSAb-IP,SDS-PAGE分析2设计恢复n/c区正电荷的双突变R6C-M5R和R6C-D20R转染293T细胞,用35SCys/Met标记,INSAb-IP,SDS-PAGE分析3应用
Background and aims Dipeptidyl peptidase IV (DPP-IV),whose substrates includes glucagon-like peptide 1 and many other polypeptides, is not only important in pancreatic β-cell regulation but also has c
Background Inactivating MEN1 mutations are the most common genetic defects present in sporadic and inherited pancreatic neuroendocrine tumors (PNETs).The lack of interventional therapies prompted us t
Background and aims Pancreatic beta ceils undergo dynamic remodeling during neonatal period to meet the increased physiological demands after weaning, with decreased proliferation,neogenesis and enhan
Objectives Either metformin or GLP-1 analogue liraglutide,which is widely used in the therapy of type 2 diabetes (T2DM),has been shown to be potentially beneficial in the management of cardiovascular
Background Anemia is a common complication in patients with diabetes, and is often attributed to overt diabetic nephropathy or impaired renal function.Recently, the association of anemia and diabetic
Objective Insulin resistance and β-cell function are different between the young and elderly diabetes individuals, which are not well elaborated in the non-diabetic ones.We compared insulin resistance
Obiective Multiple endocrine neoplasia type 1(MEN1) is usually caused by a germline mutation in MEN1 gene encoding the tumor-suppressor protein Menin.The most frequent and initial MEN1-associated endo
目的 探讨肥胖患者、糖耐量异常(IGT)、2型糖尿病患者与正常健康对照血浆胰多肽(PP)水平的变化及意义.方法 肥胖患者、IGT、2型糖尿病患者及正常对照者共47人,测定其基础、标准蛋白餐后15 min、30min、60min、120min血浆PP以及空腹血糖、胰岛素,比较并观察在肥胖患者、IGT、2型糖尿病患者中不同水平胰多肽的意义.结果 肥胖组胰多肽水平最低,IGT组及2型糖尿病组胰多肽水平升
Backgroud and Aims Accurate noninvasive prediction scores for non-alcoholic fatty liver disease (NAFLD) are demanded to screen for NAFLD in clinic.Several prediction scores have been developed, howeve