Efficient Synthesis and Stereochemical Revision of Coibamide A

来源 :中国化学会全国第十二届有机合成化学学术研讨会 | 被引量 : 0次 | 上传用户：wuhaoxin1987

【摘要】

：

　　Coibamide A is a highly N-methylated cyclodepsipeptides,which was isolated by McPhail and co-workers from a Panamanian marine cyanobacterium in 2007.Coibami

【作者】

：

Fang Lijing Yao Guiyang Pan Zhengyin Wang Wei Su Wu

【机构】

：

GuangdongKeyLaboratoryofNanomedicine,InstituteofBiomedicineandBiotechnology,ShenzhenInstitutesofAdva

【出处】

：

中国化学会全国第十二届有机合成化学学术研讨会

【发表日期】

：

2015年10期

【关键词】

：

coibamide A cyclodepsipeptide total synthesis stereochemical revision triphosgen

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　　Coibamide A is a highly N-methylated cyclodepsipeptides,which was isolated by McPhail and co-workers from a Panamanian marine cyanobacterium in 2007.Coibamide A exhibited attractive low-nanomolar inhibitory activities against the proliferation of a number of human cell lines,with a potentially new mechanism of action.

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Efficient Synthesis and Stereochemical Revision of Coibamide A

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