Cardiomyocyte-specific expression of CYP2J2 prevents development of cardiac remodeling induced by An

来源 :2014 International Symposium on Polyunsaturated Fatty Acids | 被引量 : 0次 | 上传用户：yanxt99

【摘要】

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　　Aims: Cardiac remodeling is one of the key pathological changes that occur with cardiac injury and cardiovascular disease.Previous studies have demonstrated

【作者】

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Zuowen He Xu Zhang Chen Chen Zheng Wen Samantha L.Hoopes Darryl C.Zeldin Dao Wen Wang

【机构】

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DepartmentsofInternalMedicineandInstituteofHypertension,TongjiHospital,TongjiMedicalCollege,Huazhong

【出处】

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2014 International Symposium on Polyunsaturated Fatty Acids

【发表日期】

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2014年10期

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　　Aims: Cardiac remodeling is one of the key pathological changes that occur with cardiac injury and cardiovascular disease.Previous studies have demonstrated the beneficial effects of CYP2J2 expression on cardiac injury.In the present study, we investigated the effects of cardiomyocyte-specific CYP2J2 expression and EET treatment on angiotensin Ⅱ induced cardiac remodeling and sought to determine the underlying molecular mechanisms involved in this process.

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Cardiomyocyte-specific expression of CYP2J2 prevents development of cardiac remodeling induced by An

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