【摘 要】
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Background We tried to determine whether intra-epiphyseal resection for epiphysis preservation could lead to limb discrepancy without increasing the risk of local recurrence or death in patients with
【机 构】
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Department of Orthopaedics,General Hospital of Ji' Nan Military Region,Ji' Nan 250031,China
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Background We tried to determine whether intra-epiphyseal resection for epiphysis preservation could lead to limb discrepancy without increasing the risk of local recurrence or death in patients with osteosarcoma in distal femur.Methods We retrospectively reviewed 5 children of osteosarcoma in distal femur in our institution,who underwent limb-salvage surgery of intra-epiphyseal resection for epiphysis preservation with inactivated-autograft or allograft reconstruction.They were one boy and four girls with an average age of 9.2 years(range 6–14 years).We tried to analyze the lower limb length and the complications.MSTS scores were used to analyze the functional outcomes.Results After a mean follow-up of 100 months(80-167months),all children were alive.Four patients continued to be disease-free and one experienced late post-operative recurrence.Only one child got equal limb length without any complications,who was 14 years old at the initial surgery.The other 4 children showed lower limb length discrepancies of 8,7,8 and 7cm.Conclusions As for epiphysis preservation,intra-epiphyseal resection without the preservation of the chondrocytes layer followed biological reconstruction in distal femur lead to limb discrepancy.The chondrocytes layer of physeal growth cartilage(physis)is the most important site for limb growth.This limb salvage procedure does not increase the risk of local recurrence or death in patients with osteosarcoma in distal femur.
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