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The nutritional value and key odor profile of hepatopancreas of Chinese mitten crab (Eriocheir sinensis) was evaluated,and gender differences in terms of edible yield,proximate composition,different lipid fractions,fatty acid composition and key odor compounds were compared.Total lipids were separated into different lipid fractions using silicic acid columns.And odorants were detected by monolithic material sorptive extraction (MMSE) coupled with gas chromatography-masss pectrometry-olfactometry (GC-MS-O). Furthermore, detected frequency and odor intensity method of GC-O were applied to select key odor compounds in steamed E. sinensis.