Novel Inhibitors of Lon Protease Reduce Bacterial Persister Formation

来源 :中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议 | 被引量 : 0次 | 上传用户：gouchiren424

【摘要】

：

Bacterial persister is a sub-group of special population of bacteria,and has the distinction marks from the ordinary bacteria and resistant mutants.The presence of persister is believed to be closely

【作者】

：

Qi Sun Tongqing Li Runtao Li Jianfeng Pei Luhua Lai

【机构】

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College of Chemistry and Molecular Engineering,and Center for Quantitative Biology,Peking University

【出处】

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中国生物化学与分子生物学会第十二届会员代表大会暨2018年全国学术会议

【发表日期】

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2018年10期

【关键词】

：

Lon protease Toxin-antitoxin system Persister Peptidyl boronic acid

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　　Bacterial persister is a sub-group of special population of bacteria,and has the distinction marks from the ordinary bacteria and resistant mutants.The presence of persister is believed to be closely associated with the recalcitrance and recurrence of chronic infections,and also can increase the prevalence of multidrug-resistant bacteria and extensive resistance mutation.

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Novel Inhibitors of Lon Protease Reduce Bacterial Persister Formation

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