论文部分内容阅读
Peptides and proteins are known to form a variety of ordered structures via assembling processes.The insight of the assemble peptide and protein structures could provide basis for developing diagnosis and therapeutics for neurodegenerative diseases.The documented experimental results have revealed that the capability of peptides to form ordered structures has significant dependence on the sequence.It is keen to investigate the site-specific effects due to the residues on the aggregation propensity of peptide molecules.An important subject under study is the formation mechanisms of peptide assemblies at the level of individual amino acids.