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目的 细胞命运决定因子DACH1 是多种肿瘤的新型抑癌基因。前期试验证实DACH1 启动子区域的甲基化导致其表达下降，且其表达水平与原发性肝癌的恶性进展密切相关。但具体机制亟待深入。本实验进一步探讨DACH1 在肝癌进程中的具体机制，为改善肝癌病人的预后提供科学依据。
DACH1抑制原发性肝癌的恶性侵袭与转移的机制研究
【摘 要】
：
目的 细胞命运决定因子DACH1 是多种肿瘤的新型抑癌基因。前期试验证实DACH1 启动子区域的甲基化导致其表达下降，且其表达水平与原发性肝癌的恶性进展密切相关。但具体机
【机 构】
：
华中科技大学同济医学院附属同济医院综合科 430030
【出 处】
：
第9届中国健康服务业大会暨中华医学会第七次全国健康管理学学术会议
【发表日期】
：
2015年期
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