【摘 要】
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Objective Empirical findings showed that individuals with schizotypal personality disorders (SPD) features did not presentthe significant reduction of P300 amplitude elicited by target stimulus compar
【机 构】
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Key Laboratory of Mental Health; Neuropsychology and Applied Cognitive Neuroscience Laboratory, Inst
【出 处】
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中国神经科学学会第九届全国学术会议暨第五届会员代表大会
论文部分内容阅读
Objective Empirical findings showed that individuals with schizotypal personality disorders (SPD) features did not presentthe significant reduction of P300 amplitude elicited by target stimulus compared to healthy controls.This study aimed to investigate whether emotional face would elicit the P300a and there would be reduction amplitudes for individuals with SPD as compared to healthy controls in the Chinese context.Method Preliminary ERP data including 33 participants, 16 individuals with and 17 individuals without SPD features.The procedure consisted of 1200 trials, 2 sessions and 600 trails for each session.10 percent of all stimuli were emotional face pictures, 10 percent were target stimuli and the other 80 percent were standard stimuli.The SOA in the experiment was set at 1000-1500 ms.Stimuli were presented at 500 ms.Results Target stimuli elicited the P300b both in individuals with and without SPD features.The individuals with SPD features also exhibited reduced P300b amplitudes for target stimuli as compared to those without SPD features.However, there were no significant differences of P300 latency between the two groups.Emotional face pictures were found to elicite P1 and N2 component in both groups.Conclusion The current findings extend our realization about emotional process of schizophrenia spectrum disorders.Individuals with SPD presented similar features to schizophrenia patients that P300 amplitudes were reduced.
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