内源性硫化氢抑制子宫激活的机制

来源 :中国生理学会第24届全国会员代表大会暨生理学学术大会 | 被引量 : 0次 | 上传用户：laopoxqq001

【摘要】

：

目的：硫化氢(H2S)是近年来发现的第三类气体信号分子,在体内发挥包括抗炎在内的多种生物学功能。人类分娩是一个炎症过程,分娩前夕炎性因子参与激活子宫。人类妊娠子宫平滑肌能够表达H2S 合成酶CSE 和CBS,且足月临产组H2S 合成酶的表达量明显低于足月未临产组,提示内源性H2S 可能参与抑制子宫激活。

【作者】

：

游兴姬古航倪鑫

【机构】

：

第二军医大学/生理学教研室第二军医大学/长海医院妇产科

【出处】

：

中国生理学会第24届全国会员代表大会暨生理学学术大会

【发表日期】

：

2014年7期

【关键词】

：

硫化氢子宫激活炎性因子子宫收缩相关蛋白信号转导通路

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Upregulation of cystathionine β-synthetase by toll-like receptor 4 activation contributes to viscera

Background:Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterized by abdominal pain and bloating in association with altered bowel movements.A growing body of evidence poin

会议

IBSvisceral hypersensitivitytoll-like receptor 4NF-κBCBS

Effects of dietary composition and genetic predisposition on sucrose sensitivity in SD rats

Both dietary and genetic factors contribute to individual differences in body weight regulation.The present study examined the change of sucrose sensitivity in obesity-prone (OP) rats and obesity-resi

会议

obesity proneobesity resistanthigh fat diettaste sensitivitydetection thresh

The Effect of Pulse Radiofrequency on Pain Behavior and Function of Voltage-gated Sodium Channels in

Objective: To investigate the effect of pulse radiofrequency(PRF)on pain behavior,and current densities,kinetic properties of voltage-gated sodium channels(VGSC)in dorsal root ganglion(DRG)neurons in

会议

pulse radiofrequencyDRGvoltage-gated sodium channels

Neonatal Ketamine Exposure Causes Impairment of Long-term Synaptic Plasticity in the Anterior Cingul

Ketamine,a dissociative anesthetic most commonly used in many pediatric procedures,has been reported to cause widespread neuroapoptosis in the neonatal brain after exposure in high doses and/or for pr

会议

ketamineanterior cingulate cortexlong-term potentiationexcitatory synaptic tr

CXCR4 contributes to thalamic hemorrhage-induced pain hypersensitivity via participating in the neur

Objective As a troublesome neuropathic pain,CPSP seriously affects the daily life and long-term outcomes of patients.So far,no specific treatments are clinically available for the management of CPSP,m

会议

central post stroke painthalamic hemorrhageCXCR4stromal cell-derived factor 1

The effect of different intensities of electroacupuncture on C-fiber reflex and nociceptive behavior

OBJECTIVES:This study aims to explore electroacupuncture (EA) analgesic effect by observing the sciatic C-fiber reflex and nociceptive behavior test in rats.METHODS:Experiments are conducted in 8 SD m

会议

ElectroacupunctureElectromyogramC-fiber reflexAnalgesia

Effects of Different Intervention Methods on the Protein Expression of ER and ERRα in the Uterus of

Objective The aim of this study was to compare the effects of different intervention methods on the protein expression of estrogen receptor(ERα,ERβ)and estrogen receptor related receptor α(ERRα)in the

会议

Ovariectomized ratsEstrogen receptorWhole-body vertical vibrationGenisteinTr

Cystathionine β-synthase and cystathionine γ-lyase regulate VEGF and sFlt-1 production in human plac

Imbalance release of proangiogenic and antiangiogenic factor from placenta causes maternal endothelial dysfunction,the main manifestation of preeclampsia (PE).Recently,hydrogen sulfide (H2S) has been

会议

hydrogen sulfidecystathionine β-synthasecystathionine γ-lyase regulatevascula

Accentuation of ANP secretion by physcion via L-type Ca2+ channels in isolated perfused beating rabb

Objective:Physcion,an active anthraquinone constituent isolated from the rhubarb,a traditional Chinese herbal medicine which is widely used in clinical treatment,has cardiovascular protective properti

会议

Physcionatrial natriuretic peptidesecretionL-type Ca2+channelsatrial dynamic

花生四烯酸细胞色素P450ω-羟化酶4A14在小鼠肝脏脂质代谢中的作用

目的：随着人们生活水平的提高，我国非酒精性脂肪肝的发病率越来越高。本文旨在探讨细胞色素P450 ω-羟化酶CYP4A14 在肝脏脂质代谢中的作用，以期为阐明非酒精性脂肪肝发生的机制提供线索。方法：(1)野生型(WT)及CYP4A14 基因敲除(4A14KO)小鼠分为如下四组：1)WT+普通饮食组；2)WT+高脂饮食组；3)4A14KO+普通饮食组；4)4A14KO+高脂饮食组。

会议

CYP4A14非酒精性脂肪肝FAT/CD36

内源性硫化氢抑制子宫激活的机制

其他学术论文