论文部分内容阅读
Aims: To find specific magnetic resonance imaging(MRI)features to differentiate metastatic ovarian tumors fromprimary epithelial ovarian cancers.Methods: Eleven cases with metastatic ovarian tumors and 26 cases with primary malignant epithelial ovarian cancerswere retrospectively studied.All features such as patient characteristics,MRI findings and biomarkers were evaluated.he differences including laterality,configuration,uniformity of locules,diffusion weighted imaging(DWI)signal of solidcomponents and enhancement of solid portions between metastatic ovarian tumors and primary epithelial ovarian cancers were compared by Fishers exact test.Median age of patients,the maximum diameter oflesions and biomarkers were compared by the Mann-Whitney test.Results: Patients with metastatic ovarian tumors were younger than patients with primary epithelial ovariancancers in the median age(P = 0.015).Patients with bilateral tumors in metastatic ovarian tumors were morethan those of primary epithelial ovarian cancers(P = 0.032).The maximum diameter of lesions in metastaticovarian tumors was smaller than that of primary epithelial ovarian cancers(P = 0.005).The locules in metastatic ovariantumors were more uniform than those of primary epithelial ovarian cancers(P = 0.024).The enhancement ofsolid portions in metastatic ovarian tumors showed more moderate than that of primary epithelial ovariancancers(P = 0.037).There was no statistically significant difference between the two groups in configuration,DWI signal of solid components and ascites.Biomarkers such as CA125 and human epididymis protein 4(HE4)in metastatic ovarian tumors showed less elevated than that of primary epithelial ovarian cancers.Conclusions: Significant differences between metastatic ovarian tumors and primary epithelial ovarian cancerswere found in the median age of patients,laterality,the maximum diameter of lesions,uniformity of locules,enhancement patterns of solid portions and biomarkers.Metastatic ovarian tumors usually presented in theyounger patients,smaller-sized,more bilateral lesions,more uniform of locules,more moderate enhancementof solid portions,and less elevated levels of CA125 and HE4 than those of primary epithelial ovarian cancers.