POST-TRANSCRIPTIONAL REGULATION OF INFLAMMATORY CYTOKINE EXPRESSION BY TRISTETRAPROLIN IS ESSENTIAL

来源 :The 1st NI-CMI Joint Conference(第一届CMI-NI免疫学国际研讨会) | 被引量 : 0次 | 上传用户:kkufo
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Initial exposure to lipopolysaccharide (LPS) induces endotoxin tolerance, a transient tolerance to subsequent LPS challenge.Negative regulators induced by initial LPS has been proposed to play key roles in establishing endotoxin tolerance by suppressing NF-κB activity and proinflammatory cytokine synthesis to subsequent LPS stimulation.
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