【摘 要】
:
Cytokine irnmunotherapy enhances the anti-tumor immunity and is now part of the therapeutic armamentarium for cancer treatment.We have previously reported that heavily-treated lymphoma patients have a
【机 构】
:
Indiana University-Purdue University Indianapolis (IUPUI) USA
论文部分内容阅读
Cytokine irnmunotherapy enhances the anti-tumor immunity and is now part of the therapeutic armamentarium for cancer treatment.We have previously reported that heavily-treated lymphoma patients have acquired deficiency of Signal Transducer and Activator of Transcription 4 (STAT4),which results in defective production of IFN following IL-12 irnmunotherapy.With the goal of further improvement in cytokine immunotherapy, we examined the effects of a soybean peptide called lunasin that exhibits immunostirnulatory effects.
其他文献
Zinc is known to modulate many important cellular functions including anti-inflammatory responses, and zinc acetate has been used as a therapeutic drug (called Galzin or Wilzin) for medical treatment
One of the best-characterized CD8+ regulatory T cells are CD8+CD122+regulatory T cells that were proved to play important roles in maintaining the immune homeostasis.However, CD8+CD 122+ cells also co
Most common insect allergies are due to stings by ants, bees and wasps.Many species of each of these insects are distributed worldwide.Various investigators have studied the protein and peptide compos
Rhinitis, which includes "hay fever" or seasonal allergic rhinitis, is an increasingly common chronic condition and one that is increasing around the world.The prevalence of rhinitis for adults aged b
The quantification of viral replication and immune markers in infected humans such as HIV-infected patients is very indirect and lacks anatomic definition.We hypothesized that a method able to capture
Urticaria episodes that continue for more than 6 weeks without any physical, allergic, infectious, drug-related or vasculitic cause are typically termed chronic idiopathic urticaria (CIU).It is often
Allergic disorders and skin response to histamine have been noted to vary in different ethnicities.We investigated IgE-mediated allergic sensitization and skin response to histamine in Asian Pacific A
Benazepril, an angiotensin-converting enzyme (ACE) inhibitor, has been used to treat hypertension, congestive heart failure, and chronic renal failure.However, the biological activity and mechanism of
Food derived proteases are known to have a central role in inflammatory reactions via activates protease activation receptors (PARs) on various cells types.We investigate in this study the effect of a
Adoptive cell transfer (ACT) immunotherapy for cancers using autologous in vitro expanded tumorinfiltrating lymphocytes (TIL) can induce immune response and anti-tumor activity in vivo in patients wit