CREG over-expression in BMSC protects against myocardial infarction via VHL/HIF-1α/VEGF pathway medi

来源 :第十二届中国介入心脏病学大会(CIT2014) | 被引量 : 0次 | 上传用户：dlxfmc

【摘要】

：

【作者】

：

Peng Chengfei Tian Xiaoxiang Deng Jie Wang Jie Yan Chenghui Li Yang Tao Jie Han Yaling

【机构】

：

The First Affiliated Hospital of Soochow University,Shenyang,Liaoning,China

【出处】

：

第十二届中国介入心脏病学大会(CIT2014)

【发表日期】

：

2014年3期

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Background We hypothesized that mesenchymal stem cells (MSCs) overexpressing Cellular Repressor of E1A-stimulated Genes (CREG) showed improved survival and engraftment in the infarcted heart and promoted vascularization through paracrine release of vascular endothelial growth factor (VEGF) and activation of the HIF-1α signal pathway.

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CREG over-expression in BMSC protects against myocardial infarction via VHL/HIF-1α/VEGF pathway medi

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