【摘 要】
：
研究背景：我国85％以上的肝衰竭是由HBV感染引起的,其中慢加急性肝衰竭(acute-on-chronic liver failure,ACLF)和慢性肝衰竭(chronic liver failure,CLF)是最常见的两个类型
【出 处】
：
第二十四次全国中西医结合肝病学术会议
论文部分内容阅读
研究背景：我国85％以上的肝衰竭是由HBV感染引起的,其中慢加急性肝衰竭(acute-on-chronic liver failure,ACLF)和慢性肝衰竭(chronic liver failure,CLF)是最常见的两个类型,其病情严重、并发症复杂、致死率极高。乙肝表面抗原(HBsAg)是HBV的外壳蛋白,在HBV感染和致病机制中发挥重要作用。乙肝e抗原(HBeAg)是HBV在体内复制活跃的标志之一,其发生血清学转换意味着HBV复制活性降低或病毒变异,是常用的评估病情的指标。乙肝核心抗体(HBcAb)可用作HBV感染和病毒复制的良好指标,通常用于临床诊断和血液筛查。终末期肝病模型(model for end-stage liver disease,MELD)被广泛用于评价终末期肝病的严重程度和预测预后转归情况,因此,本文旨在探究上述三项指标水平在CHB、ACLF、CLF患者中的变化,及其与MELD评分有无相关性。
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