‘Fastening’ Dyes into the Cross-linked Polyphosphazene:a New Type of Fluorescent Nanoparticles for M

• 作 者: 孟令杰;
• 机 构: 西安交通大学
• 出 处: 第六届海内外中华青年材料科学技术研讨会暨第十五届全国青年材料科学技术研讨会
• 发表日期: 2015年期

　　It is a significant issue to overcome the concentration-quenching effect of the small fluorescent probes and maintain the high fluorescent efficiency at high concentration for sensitive and selective fluorescent mark or detection.We developed a new strategy to isolate and fasten fluorescent moieties into a highly cross-linkcd polyphosphazene(PZS).The resulting fluorescent PZS nanoparticles can emit bright fluorescence both in powder state and in solution because the aggregation of fluorescent moieties in "H-type"(face-to-face)and "J-type"(edge-to-edge)was effectively blocked.The fluorescent PZS nanoparticles also showcd superior resistance to photobleaching,protein interferes,and had a high sensitivity and selectivity for the detection of dopamine and Hg2+ ions,respectively.The fluorescent nanoparticles were therefore acted as an ideal material for preparing test strips to quickly detect/monitor the dopamine and Hg2+ ions in a facile way.In addition,the DBF-PZS also showed low toxicity and could be also used for bioimaging.