【摘 要】
：
Indolo[2,1-α isoquinoline is one of the most attractive frameworks with a wide range of biological and pharmacological activities(Figure 1).1 Herein,we described a visible-light induced formal [4+1] a
【机 构】
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School of Chemistry and Chemical Engineering,Sun Yat-Sen University,135 Xingang West Road,Guangzhou
【出 处】
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第五届岭南有机化学论坛暨华南理工大学-兰州大学有机化学双边论坛
论文部分内容阅读
Indolo[2,1-α isoquinoline is one of the most attractive frameworks with a wide range of biological and pharmacological activities(Figure 1).1 Herein,we described a visible-light induced formal [4+1] annulation between N-aryl tetrahydroisoquinolines and diazo compounds.2 This reaction allows the assembly of biologically important indolo[2,1-a]isoquinolines with a wide range of functional groups via the cleavage of four C-H bonds,including two sp3 C-H and one sp2 C-H bonds,under mild and metal-free conditions.
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