【摘 要】
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Object Photodynamic therapy (PDT) is a regulatory approved modality for treating a variety of malignant.It utilizes the destructive power of reactive oxygen species generated via visible light irradia
【机 构】
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State Key Laboratory of Bioreactor Engineering & Shanghai Key Laboratory of Chemical Biology,School
【出 处】
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2013医学前沿论坛暨第十三届全国肿瘤药理与化疗学术会议
论文部分内容阅读
Object Photodynamic therapy (PDT) is a regulatory approved modality for treating a variety of malignant.It utilizes the destructive power of reactive oxygen species generated via visible light irradiation of a photosensitive dye,to induced oxidative stress and bring about their obliteration.The photosensitizers used in the process of photodynamic therapy play an important role in its antitumor effect.Hence,its necessary to develop a stable cell model with high-specificity and sensitivity to assess the activity of photodynamic therapy in vitro and screen antitumor lead compounds with ideal photoacitivity.
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