【摘 要】
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In recent years,"compact molecules" e.g.4-membered hetereocyclic compounds have received increased attention in pharmaceutical industry because of the uniqueness in the generation of IP position,as we
【机 构】
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School of Pharmacy,Fudan University,Shanghai,201203,P.R.China
【出 处】
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2013医学前沿论坛暨第十三届全国肿瘤药理与化疗学术会议
论文部分内容阅读
In recent years,"compact molecules" e.g.4-membered hetereocyclic compounds have received increased attention in pharmaceutical industry because of the uniqueness in the generation of IP position,as well as adjustment of physical properties e.g.solubility,permeability,and safety related properties.The bottle necks of the application of such "compact molecules" are the difficult synthesis and scale-up.
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