【摘 要】
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In Clathrin-mediated endocytosis, Clathrin assembles into a soccerball-like structure at the plasma membrane, that was proposed to deform the membrane by scaffo
【机 构】
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DepartmentofBiochemistry,UniversityofGeneva,Geneva,Switzerland
【出 处】
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8th IUPAP International Conference on Biological Physics(第八届
论文部分内容阅读
In Clathrin-mediated endocytosis, Clathrin assembles into a soccerball-like structure at the plasma membrane, that was proposed to deform the membrane by scaffolding.However, it is not known if clathrin polymerization force is sufficient to curve the membrane, or deformation by other means (protein insertion) is required.We studied the formation of Clathrin buds from Giant Unilamellar Vesicles, and found that the pits can be flattened when membrane tension is increased.
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