PACAP induces internalization of serotonin 2A receptor in a protein kinase C-dependent manner

来源 :中华医学会第十一次全国精神医学学术会议暨第三届亚洲神经精神药理学术会议 | 被引量 : 0次 | 上传用户：xiaopirate

【摘要】

：

　　Objective Accumulating evidence from human genetic and animal model studies implicates the pituitary adenylate cyclase-activating polypeptide (PACAP) signal

【作者】

：

AtsukoHayata[1]NaokiEncho[2]KeitaMoriguchi[2]TomohiroFujino[2]NorihitoShintani[2]AtsushiKasai[3]AkemichiBaba[4]HitoshiHashimoto[5]

【机构】

：

Laboratory of Molecular Neuropharmacology,Graduate School of Pharmaceutical Sciences,Osaka Universit

【出处】

：

中华医学会第十一次全国精神医学学术会议暨第三届亚洲神经精神药理学术会议

【发表日期】

：

2013年期

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　　Objective Accumulating evidence from human genetic and animal model studies implicates the pituitary adenylate cyclase-activating polypeptide (PACAP) signaling pathway as a risk factor for psychiatric disorders,including schizophrenia and stress-related disorders.PACAP-deficient mice exhibit remarkable behavioral and neurological changes that are thought to be endophenotypes for psychiatric disorders.

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PACAP induces internalization of serotonin 2A receptor in a protein kinase C-dependent manner

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