Modeling Sequence Heterogeneity Through Maximum-Likelihood Model Averaging

• 作 者: Zhang Zhang Jeffrey P.Townsend
• 机 构: DepartmentofEcologyandEvolutionaryBiology,YaleUniversity,NewHaven,CT06520,USA
• 出 处: 2009第四届国际基因组学大会)
• 发表日期: 2009年11期
• 关键词: sequence heterogeneity maximum-likelihood model averaging divide-and-conquer

Discrete linear sequences such as DNA or protein frequently exhibit heterogeneity.Heterogeneity may include non-uniformity of polymorphic sites,substitutions,nucleotide/codon composition,selective pressure,etc.