With the transition from evidence-based medicine to precision one,cancer has entered the era of personalized treatment under the guidance of molecular typing.Therefore,the search for efficient target
The transcriptional coactivator Yes-associated protein(YAP)is frequently found dysregulated in various cancers.Targeting YAP has been established to suppress tumorigenesis.
Hypoxic tumours are a major problem for cancer photodynamic therapy.1 We discovered an efficient photo-redox catalysis which introduces a novel oxygen-independent mechanism of action to combat this pr
The increasing appearance of drug-resistant bacteria has posed great threat to human health.Innovative strategies are needed to discover alternatives to classical antibiotics and to identify novel ant
Patients with cancer have limited treatment options,since some the diseases do not respond to endocrine or targeted therapies.Approximately 15%of breast cancers are classified as triple negative,which
Accelerating the clearance of intracellular protein aggregates represents a viable approach for the treatment of neurodegenerative diseases.We have previously demonstrated enhanced degradation of muta