Study of Pharmacokinetic Interaction between Glibenclamide and Puerarin in Rats Based on UPLC-MS/MS

• 作 者: NingLi;DanWang;YingQiao;MinyanJiang;JingWen;FameiLi;
• 机 构: Department of Analytical Chemistry, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang
• 出 处: 第2届大连国际色谱学术报告会、第37届国际高效液相色谱及相关技术会议、第18届全国色谱学术报告会
• 发表日期: 2011年期

　　Glibenclamide is the second generation oral sulfonylurea anti-diabetic agent which is one of the most common adulterant in Chinese medicines used for diabetes.Puerarin is an active constituent of Pueraria lobata (Willd) Ohwi which is included in many Chinese medicines used for diabetes.They may be co-administered unwittingly or wittingly.