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In the present study, point prevalence, association of various risk factors and haematological alterations due to bovine anaplasmosis in Sahiwal and crossbred cattle of the district Faisalabad was studied.Moreover, efficacy of combinations Oxytetracycline with Imidocarbdipropionate and Enrofioxacin with Imidocarbdipropionate against Anaplasmamarginale was determined.