【摘 要】
:
近年来,我国高尿酸血症的患病率逐年上升,已达到10%左右.在代谢病患者中,合并高尿酸血症的患者更多:糖尿病患者中有25%合并患有高尿酸血症;高血压患者中约35%患有该疾病.有众多
【出 处】
:
2013中国医师协会内分泌代谢科医师分会年会
论文部分内容阅读
近年来,我国高尿酸血症的患病率逐年上升,已达到10%左右.在代谢病患者中,合并高尿酸血症的患者更多:糖尿病患者中有25%合并患有高尿酸血症;高血压患者中约35%患有该疾病.有众多国内外研究显示,高尿酸血症与多个靶器官的损害密切相关.尿酸盐沉积于关节,会造成痛风性关节炎,最终导致关节变形;沉积于肾脏,会导致痛风性肾病及尿酸结石,最终会引发尿毒症;尿酸盐结晶会刺激血管壁,导致动脉粥样硬化,最终引发冠心病、高血压、恼卒中;当尿酸盐沉积于胰岛,可导致β细胞功能损害,诱发和加重胰岛素抵抗,引起糖代谢紊乱,最终导致糖尿病.
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