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  5. Sodium channel beta subunits and extracellular matrix modulating mirror image pain induced by scorpi

Sodium channel beta subunits and extracellular matrix modulating mirror image pain induced by scorpi

来源 :第12届生物毒素研究及医药应用学术大会 | 被引量 : 0次 | 上传用户：liyongdede
【摘 要】
：
　　Voltage-gated sodium (Nay) channels play key roles in induction, transmission,transduction of pathological pain.Nay channels are composed of a pore-forming
【作 者】
：
Xia Liu Qing-Hu Yang Xiao-Xia Zhao Hong-Ni Zhu Yan-Yan Wu Xiang-Xiang Chen Lei Xi Cheng-Hui Cao Sui-Bin Ma Ke-Ke Ren Xu Wang Zhi-Hong Sun Zhan-Tao Bai 
【机 构】
：
CollegeofLifeSciences&ResearchCenterforPolypetideDrugs,YananUniversity,Yanan716000,China;ShaanxiEngi
【出 处】
：
第12届生物毒素研究及医药应用学术大会
【发表日期】
：
2015年10期
【关键词】
：
Scorpion sting Voltage-gated sodium channels Beta subunits Mirror image pain Cho 
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　　Voltage-gated sodium (Nay) channels play key roles in induction, transmission,transduction of pathological pain.Nay channels are composed of a pore-forming α subunit and associated β subunits.Each of β subunit (β1-β4)isa single membrane-spanning glycoprotein with one Ig-like motif in their extracellular domains, which may bind to Chondroitin sulfate proteoglycans (CSPGs).
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